Northwestern University Feinberg School of Medicine

Center for Genetic Medicine

Chromatin Structure/Gene Expression

Anderson, Wayne F

Anderson, Wayne F

Professor of Biochemistry and Molecular Genetics

wf-anderson( at )northwestern.edu

Description of Interests

Structural Genomics, X-ray crystallography, Protein-nucleic acid interactions

Brannigan, Robert E

Brannigan, Robert E

Professor of Urology

Description of Interests

Dr. Robert E. Brannigan's clinical concentration is male reproductive medicine and surgery. His surgical interests included performing: microsurgical vasectomy reversal; microsurgical varicocelectomy;... [more]

Bulun, Serdar E

Bulun, Serdar E

Professor of Obstetrics and Gynecology (Reproductive Science in Medicine)

nmahmood( at )nm.org

Description of Interests

The laboratory research of Serdar E. Bulun, MD, focuses on studying estrogen biosynthesis and metabolism, in particular aromatase expression, in hormone-dependent human diseases such as breast cancer,... [more]

Burridge, Paul W

Burridge, Paul W

Assistant Professor of Pharmacology

paul.burridge( at )northwestern.edu

Description of Interests

We study the application of patient-specific human induced pluripotent stem cells in studying the role of the genome in influencing drug responses, a field known as pharmacogenomics or personalized me... [more]

Carvill, Gemma L

Carvill, Gemma L

Assistant Professor of Neurology - Ken and Ruth Davee Department and Pharmacology

Description of Interests

The primary aim of our research is to identify the genetic factors and biological mechanisms that cause epilepsy. We use a variety of sequencing technologies to identify new genetic causes in both the... [more]

Choi, Jaehyuk

Choi, Jaehyuk

Assistant Professor of Dermatology and Biochemistry and Molecular Genetics

jaehyuk.choi( at )northwestern.edu

Description of Interests

We employ cutting-edge genomics approaches to identify the genetic basis of inherited and acquired immunological disorders and skin cancer. As an example, we have recently identified the genes and m... [more]

Datta, Syamal K

Datta, Syamal K

Professor Emeritus of Medicine (Rheumatology)

skd257( at )northwestern.edu

Description of Interests

Autoimmunity & Tolerance to Nucleosomes, Apoptosis, Peptide Epitope Therapy, Signaling Threshold, Lupus.

DiDonato, Christine J

DiDonato, Christine J

Associate Professor of Pediatrics (Human Molecular Genetics)

c-didonato( at )northwestern.edu

Description of Interests

My broad research interest lies in understanding the molecular basis of human genetic diseases and developing therapeutics for their treatment. Specifically, my research primarily focuses on neuromusc... [more]

Engman, David

Engman, David

Adjunct Professor of Pathology and Microbiology-Immunology

d-engman( at )northwestern.edu

Description of Interests

The Engman Laboratory conducts research in several areas: (1) Molecular genetics and cell biology of tropical parasitic infections with a focus on trypanosomes, single-celled eukaryotic pathogens cau... [more]

Horvath, Curt M

Horvath, Curt M

Professor of Weinberg College of Arts and Sciences, Medicine (Hematology/Oncology) and Microbiology-Immunology

horvath( at )northwestern.edu

Description of Interests

Interferon, STAT

Huang, Sui

Huang, Sui

Associate Professor of Cell and Molecular Biology

s-huang2( at )northwestern.edu

Description of Interests

Nucleolus, nucleus, chromatin, nuclear structure and function, cancer, growth-regulations, signal-transductions,

Kansas, Geoffrey S

Kansas, Geoffrey S

Associate Professor of Microbiology-Immunology

gsk( at )northwestern.edu

Description of Interests

My laboratory is interested in transcriptional control of leukocyte traffic during inflammation and immunity. Our focus is on glycosyltransferase genes which encode enzymes which contribute to the bi... [more]

Kearney, Jennifer A

Kearney, Jennifer A

Associate Professor of Pharmacology

jennifer.kearney( at )northwestern.edu

Description of Interests

Research in my laboratory is focused on studying genetic modifiers that influence the clinical severity of epilepsy. Variable expressivity is a common feature in patients with epilepsy caused by sodiu... [more]

Kohtz, Jhumku D

Kohtz, Jhumku D

Research Professor of Pediatrics (Developmental Biology)

j-kohtz( at )northwestern.edu

Description of Interests

I have had a long-standing interest in studying RNA regulatory mechanisms in development. My lab has focused on studying the mechanism of action of Evfs, novel long non-coding RNAs that regulate trans... [more]

Kosak, Steven T

Kosak, Steven T

Assistant Professor of Cell and Molecular Biology

s-kosak( at )northwestern.edu

Kume, Tsutomu

Kume, Tsutomu

Professor of Medicine (Cardiology) and Pharmacology

Description of Interests

Dr. Kume's research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovasc... [more]

LaBonne, Carole

LaBonne, Carole

Director, Interdepartmental Program in Biological Sciences (IBiS) Professor of Molecular Biosciences Weinberg College of Arts and Sciences

clabonne( at )northwestern.edu

Description of Interests

Our lab uses molecular genetic and genomic approaches to study the development of a group of embryonic cells called the neural crest. Neural crest cells are migratory, tissue-invasive stem cells that originate in the ectoderm of vertebrate embryos and play a central role in the development of the vertebrate body plan.

Laimins, Laimonis A

Laimins, Laimonis A

Professor of Microbiology-Immunology

Description of Interests

papillomaviruses, cervical cancer, epithelila cells, diffrentiation

Ma, Yongchao

Ma, Yongchao

Assistant Professor of Pediatrics (Developmental Biology), Neurology - Ken and Ruth Davee Department and Physiology

ma( at )northwestern.edu

Description of Interests

Regulation of Motor Neuron and Dopaminergic Neuron Function in Development and Disease -------- Spinal Motor Neurons and Spinal Muscular Atrophy (SMA): SMA is characterized by the selective degenerati... [more]

Mayo, Kelly

Mayo, Kelly

Associate Dean for Research and Graduate Studies Professor of Molecular Biosciences Weinberg College of Arts and Sciences

k-mayo( at )northwestern.edu

Description of Interests

Stochastic and discrete optimization algorithms; decision under uncertainty; healthcare systems; portfolio optimization

Meeks, Joshua J

Meeks, Joshua J

Assistant Professor of Urology and Obstetrics and Gynecology

Description of Interests

Dr. Meeks is an Assistant Professor of Urology at the Northwestern University Feinberg School of Medicine, as well as Section Chief of Robotic Surgery at the Jesse Brown VA Medical Center. He received... [more]

Mendillo, Marc L

Mendillo, Marc L

Assistant Professor of Biochemistry and Molecular Genetics

mendillo( at )northwestern.edu

Description of Interests

The cellular protein homeostasis network guards the proteome from diverse endogenous and environmental insults to maintain the fitness of the organism. Ironically, this pro-survival network can act to... [more]

Morimoto, Richard I

Morimoto, Richard I

Bill and Gayle Cook Professor of Biology Director, Rice Institute for Biomedical Research Department of Molecular Biosciences Weinberg College of Arts and Sciences

r-morimoto( at )northwestern.edu

Description of Interests

Our laboratory is interested in the fundamental events that underlie the appearance of misfolded proteins and their consequence to protein homeostasis, cellular function, and organismal adaptation and survival

Opal, Puneet

Opal, Puneet

Professor of Neurology (Movement Disorders) and Cell and Molecular Biology

Description of Interests

Ataxias, spinocerbellar ataxia, movement disorders, neurodegenerative diseases, stroke, cerebrovascular disorders.

Pachman, Lauren M

Pachman, Lauren M

Professor of Pediatrics (Rheumatology)

pachman( at )northwestern.edu

Description of Interests

Dr. Pachman's translational team studies Juvenile Myositis (JM), an often chronic pediatric systemic vasculopathy associated with skin inflammation and proximal muscle weakness of unknown etiology. He... [more]

Payne, Christopher J

Payne, Christopher J

Assistant Professor of Pediatrics (Human Molecular Genetics) and Obstetrics and Gynecology

c-payne( at )northwestern.edu

Description of Interests

My lab focuses on how genetic and epigenetic modulators promote the development and maintenance of adult stem cells. Microenvironments, or niches, support the maintenance of stem cells and facilitate ... [more]

Radhakrishnan, Ishwar

Radhakrishnan, Ishwar

Professor of Molecular Biosciences

i-radhakrishnan( at )northwestern.edu

Description of Interests

Large molecular assemblies comprising multiple protein and/or nucleic acid subunits perform a variety of specialized tasks in the cell. Research in the Radhakrishnan laboratory is directed towards clarifying the structural and thermodynamic bases of protein-protein and protein-DNA interactions that regulate the formation and/or recruitment of these molecular assemblies.

Rundell, Kathleen

Rundell, Kathleen

Professor Emeritus of Microbiology-Immunology

krundell( at )northwestern.edu

Description of Interests

transformation, mesothelioma, cyclins, phosphatases, apoptosis, transactivation

Saratsis, Amanda Muhs

Saratsis, Amanda Muhs

Assistant Professor of Neurological Surgery

Description of Interests

Dr. Saratsis has clinical appointments in the Departments of Neurological Surgery at Northwestern Memorial and Lurie Children's Hospitals, caring for children and adults with congenital disorders of t... [more]

Tourtellotte, Warren G

Tourtellotte, Warren G

Professor of Pathology and Neurology - Ken and Ruth Davee Department

warren( at )northwestern.edu

Description of Interests

Anatomic Pathology, Neuropathology, Neuromuscular pathology<BR><BR> The early growth response (Egr) family of transcription factors are involved in cellular growth and differentiation and may play a ... [more]

Woloschak, Gayle E

Woloschak, Gayle E

Professor of Radiation Oncology and Radiology

g-woloschak( at )northwestern.edu

Description of Interests

My research is focused on two general areas: radiobiology and bionanotechnology. Work in radiobiology includes studies of the molecular biology of radiation responses, particularly radiation toxicitie... [more]

Wu, Jane Y

Wu, Jane Y

Professor of Neurology (Neuromuscular Disease)

Description of Interests

My primary research interests are in molecular mechanisms of gene regulation, particularly those involved in neural development and neural degeneration. My lab is focusing on two areas, RNA regulation... [more]

Yang, Guang-Yu

Yang, Guang-Yu

Professor of Pathology

g-yang( at )northwestern.edu

Description of Interests

Surgical Pathology<BR><BR> The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are... [more]

Yu, Jindan

Yu, Jindan

Associate Professor of Medicine (Hematology/Oncology) and Biochemistry and Molecular Genetics

jindan-yu( at )northwestern.edu

Description of Interests

The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinfo... [more]

Zhang, Wei

Zhang, Wei

Associate Professor of Preventive Medicine (Cancer Epidemiology and Prevention)

wei.zhang1( at )northwestern.edu

Description of Interests

Dr. Zhang's major research interests include the genetics and epigenetics of complex traits, such as risks for common diseases, drug response, and gene expression. Dr. Zhang is also developing novel e... [more]