Northwestern University Feinberg School of Medicine

Center for Genetic Medicine

Jaehyuk  Choi, MD, PhD

Jaehyuk Choi, MD, PhD

Ruth K. Freinkel, MD, Research Professor

Assistant Professor of Dermatology and Biochemistry and Molecular Genetics

Contact

312-503-4108

Robert H Lurie Medical Research Center Room 5-115
303 E Superior
Chicago IL 60611

jaehyuk.choi( at )northwestern.edu

Education/Research Website

Hospital Affiliations

I am on the medical staff at the following Feinberg-affiliated hospital(s)

Education and Certification

PhD: Yale University, Immunology (2006)
MD: Yale University School of Medicine (2006)
Residency: Yale University, Dermatology (2010)
Postdoctoral Fellowship: Yale University, Genetics (2012)

Interests

Description of Interests

We employ cutting-edge genomics approaches to identify the genetic basis of inherited and acquired immunological disorders and skin cancer. As an example, we have recently identified the genes and mutations underlying cutaneous T cell lymphoma, an incurable non-Hodgkin lymphoma of skin-homing T cells. The genes are components of the DNA damage, chromatin modifying, NF-B, and the T cell receptor signaling pathways. We are currently employing a comprehensive approach using human tissues and animal models to investigate the functions of these genes. We are confident these studies will allow us to elucidate the pathophysiology of this cancer and lead to the identification of novel therapeutic targets. News: http://scitechdaily.com/yale-study-shows-t-cell-lymphoma-caused-by-gene-deletions/ https://www.genomeweb.com/sequencing-technology/comprehensive-sequencing-ids-genes-involved-cutaneous-t-cell-lymphoma

Interests (Keywords)

Cancer: Skin; Cutaneous T-Cell Lymphoma; Dermatology; Genetics; Immunogenetics; Immunology; Melanoma

Research and Publications

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Institutes and Centers

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Disclosures

 

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