Northwestern University Feinberg School of Medicine

Center for Genetic Medicine

Marc L Mendillo, PhD

Marc L Mendillo, PhD

Assistant Professor of Biochemistry and Molecular Genetics



Morton Building Room 7-643
310 E Superior
Chicago IL 60611

mendillo( at )

Education/Research Website

Education and Certification

PhD: University Of California-San Diego, Biomedical Sciences (2007)
Postdoctoral Fellowship: Ludwig Institute for Cancer Research, San Diego, CA, Cancer Research (2008)
Postdoctoral Fellowship: Whitehead Institute (2015)


Description of Interests

The cellular protein homeostasis network guards the proteome from diverse endogenous and environmental insults to maintain the fitness of the organism. Ironically, this pro-survival network can act to the detriment of the host to enable tumor cells accommodate to the myriad stresses associated with malignancy. Our long-term goals are to identify and characterize the systems that promote protein homeostasis, understand how these systems are co-opted and perturbed in malignancy, and ultimately identify means to manipulate them for therapeutic benefit. To accomplish these goals our group bridges biochemical, genetic and chemical biology approaches with systematic high-throughput and genomic methods.

Interests (Keywords)

Cancer Biology; Cell Biology; Energy Metabolism; Epigenetics; Gene Regulation; Genetics; Genomics; Systems Biology

Research and Publications

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