Northwestern University Feinberg School of Medicine

Center for Genetic Medicine

Guang-Yu  Yang, MD, PhD

Guang-Yu Yang, MD, PhD

Joseph C. Calandra Research Professor of Pathology and Toxicology

Professor of Pathology



Ward Building Room Ward 4-115
303 E Chicago Avenue
Chicago IL 60611

g-yang( at )

Hospital Affiliations

I am on the medical staff at the following Feinberg-affiliated hospital(s)

Education and Certification

MD: China Medical University (1983)
PhD: China Medical University, Molecular Pathology (1992)
Residency: New York University Medical Center (2004)
Fellowship: Johns Hopkins Hospital (2005)
Board Certification: Anatomic Pathology & Clinical Pathology


Description of Interests

Surgical Pathology

The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.

Interests (Keywords)

Cancer Biology; Cancer: Digestive System (esophagus, stomach, colon, and rectum); Inflammatory Bowel Disease; Liver disease, pathobiology; Pancreatic disorders; Pathology

Research and Publications

Northwestern Scholars

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Institutes and Centers

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